Current Studies

The goal of this clinical trial is to learn about cognition in schizophrenia, bipolar disorder, and schizoaffective disorder using MRI scans and Transcranial Magnetic Stimulation (TMS)

Seeking individuals between 18-35 with a diagnosis of a psychotic disorder with an onset within 3 years. We are interested in understanding how we can predict outcomes using assessments of symptoms, thinking abilities, and brain function.

We want to understand how people with schizophrenia and bipolar disorder understand their bodily signals and how these signals may affect their perception of and interaction with the outside world.

This study examines the impact of transcranial magnetic stimulation (TMS) on brain energy metabolism in people with bipolar disorder. The study includes a baseline visit, five days of TMS, and a follow-up visit.

We are studying whether your diet can have an effect on energy pathways in the brain and can improve cognition, mood, and psychosis. There is evidence for diet modification being beneficial in other conditions such as epilepsy. In this study, we will compare the ketogenic diet and a standard diet and their effects on brain energy.

Help researchers assess nutritional supplement Magnesium-vitamin B6 in treating symptoms of anxiety, depression and stress. Participants will take Magnesium-vitamin B6 for 4 weeks and complete clinical interview, MRI scans, and blood draws.

This study looks at a treatment option for auditory hallucinations and use transcranial magnetic stimulation (TMS) to stimulate areas of the brain associated with these symptoms.

McLean Hospital researchers are seeking participants for a study that examines the role of brain functions underlying sleep characteristics. Study includes a daytime nap, memory task, and an MRI scan.

We are conducting this study to look at how the brains of healthy people use energy compared to people who are experiencing new changes in their mental health, thinking, and/or everyday functioning. We will be using an MRI scanner, a machine that uses a magnetic field and radio waves to describe your brain. 

In this study, we are investigating how things like stress and reward are processed in the brain differently for young people who are healthy, or who have begun feeling sad, down, or depressed in the past year.

This study looks at a treatment option for auditory hallucinations and use transcranial magnetic stimulation (TMS) to stimulate areas of the brain associated with these symptoms.

A study about stress and learning in the brains of teenagers and young adults. Participants answer questions about their mental health, take a cognitive assessment, and complete an MRI.

We are conducting this study to understand visual perceptual changes in adolescents and young adults with mental health concerns. We are studying visual changes in individuals who are at clinical high risk for psychosis, individuals with a history of mental health related illnesses, and individuals with no history of mental health related illnesses.